German group publishes the structure of SARS protein in a online journal, "Science Express".

In order to accelerate the studies to develop drugs to treat SARS, In-Silico Sciences Inc. has started to offer the predicted structural data of the SARS proteins for free-of-charge, at 17:00, May 9 2003 (3:00, May 9 in NY). In addition, SGI Japan has published a press release about the service of offering the predicted structural data of the SARS proteins for free-of-charge at 13:00, May 12 2003 (23:00, May 11 in NY). In a online journal, Science Express, on May 13, 2003, a paper about SARS protease model structures by Anand et al.

K. Anand, J. Ziebuhr, P. Wadhwani, J. R. Mesters, R. Hilgenfeld, 14 April 2003; accepted 12 May 2003; Published online 13 May 2003; 10.1126/science.1085658.

In the paper, they wrote "Atomic coordinates for the crystal structures of HCoV 229E Mpro and the inhibitor complex of TGEV Mpro as well as for the model of SARS-CoV Mpro have been deposited with the RCSB Protein Data Bank under accession codes 1P9S, 1P9U, and 1P9T." However, at this moment, 19:00, May 14 2003 (5:00, May 14 2003, in NY), the positional data are not available in PDB. Therefore In-Silico Sciences Inc. is the first in the world, to publish the model structures of the SARS proteins.

Copyright (C) 2003 In-Silico Sciences Inc. All Rights Reserved